It remains possible that the above examples of DE * are divergent forms of E and / or D, or the result of a back mutation.
2.
Daughter cells that inherit these wrong bases carry mutations from which the original DNA sequence is unrecoverable ( except in the rare case of a back mutation, for example, through gene conversion ).
3.
In late prehistoric Old English, back mutation changed short front " i, e, ?" to short diphthongs spelled " io, eo, ea " before a back vowel in the next syllable, if the intervening consonant is of a certain nature.
4.
The interpretations and for " ea " and " eo " are generally accepted ( evidence for the former comes, for example, from the behavior of breaking and back mutation as described below, and the Middle English development of " ea " into ).
5.
The frequency p = p _ { AA } + p _ { AB } of normal alleles " A " increases at rate 1 / ( 1-s p _ { BB } ) due to the selective elimination of recessive homozygotes, while mutation causes p to decrease at rate 1-\ mu ( ignoring back mutations ).
6.
One locus, i . e ., mitochondrial DNA, contradicts the strict monophyly of Coronaves ( Morgan-Richards et al . 2008 ), but phylogeny reconstruction based on mitochondrial DNA is complicated by the fact that few families have been studied, the sequences are heavily saturated ( with back mutations ) at deep levels of divergence, and they are plagued by strong base composition bias.
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